Skin and Skin Structure Infections

Skin and skin structures are among the most frequent sites of human bacterial infection. They represent one of the most common indications for antibiotic therapy and account for ∼10% of hospital admissions in the US.

Skin and skin structure infections involving abnormal skin or wounds, occurring in compromised hosts (such as patients with compromised immune systems or peripheral arterial disease), or requiring surgical intervention, are among the most difficult to treat, as they frequently involve gram-negative and anaerobic bacteria.

Based on Locilex®‘s broad spectrum, bactericidal activity, and excellent safety profile, we are evaluating its potential development in a variety of skin and skin structure infections, such as moderate diabetic foot infections, infected surgical wounds, infected burns, and infected decubitus ulcers (pressure sores).